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  • 유창식 교수

    외과학

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    전공분야

    대장항문외과

    소속연구단

    관련/관심분야

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    주요논문

    1. Deciphering the DNA methylation landscape of colorectal cancer in a Korean cohort [ BMB REPORTS ] - 2023.10.31
    2. Cumulative incidence and risk factors for pouch adenomas associated with familial adenomatous polyposis following restorative proctocolectomy [ WORLD JOURNAL OF GASTROENTEROLOGY ] - 2022.08.14
    3. Clostridium difficile infection after ileostomy closure and anastomotic failure in rectal cancer surgery patients [ Bjs Open ] - 2022.04.01
    4. Molecular characterization of dysplasia-initiated colorectal cancer with assessing matched tumor and dysplasia samples [ Annals of Coloproctolgy ] - 2022.02.23
    5. Treatment Strategy for Perianal Fistulas in Crohn Disease Patients: The Surgeon’s Point of View [ Annals of Coloproctolgy ] - 2021.02.08
    6. A Nine-Gene Signature for Predicting the Response to Preoperative Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer [ Cancers ] - 2020.03.26
    7. Isolated vaginal metastasis from stage I colon cancer: A case report [ World Journal of Clinical Cases ] - 2020.02.06
    8. The Influence of Preoperative Medications on Postoperative Complications in Patients After Intestinal Surgery for Crohn’s Disease [ INFLAMMATORY BOWEL DISEASES ] - 2019.09.01
    9. Signet ring cell component predicts aggressive behaviour in colorectal mucinous adenocarcinoma [ PATHOLOGY ] - 2019.06.01
    10. Local excision in mid-to-low rectal cancer patients who revealed clinically total or near-total regression after preoperative chemoradiotherapy; a proposed trial [ BMC CANCER ] - 2019.04.29
    11. Depression and resilience in ulcerative colitis and Crohn's disease patients with ostomy [ International Wound Journal ] - 2019.03.01
    12. Intestinal endometriosis: Diagnostic ambiguities and surgical outcomes [ WORLD JOURNAL OF CLINICAL CASES ] - 2019.02.26
    13. Impact of a Multidisciplinary Team Approach for Managing Advanced and Recurrent Colorectal Cancer [ WORLD JOURNAL OF SURGERY ] - 2018.07.01
    14. Risk factors for postoperative recurrence after primary bowel resection in patients with Crohn's disease. [ WORLD JOURNAL OF GASTROENTEROLOGY ] - 2017.10.14
    15. The long-term outcomes of recurrent adhesive small bowel obstruction after colorectal cancer surgery favor surgical management. [ MEDICINE ] - 2017.10.01
    16. Prediction of radio-responsiveness with immune-profiling in patients with rectal cancer [ ONCOTARGET ] - 2017.07.25
    17. Factors affecting the postoperative morbidity and survival of patients with liver cirrhosis following colorectal cancer surgery. [ INTERNATIONAL JOURNAL OF COLORECTAL DISEASE ] - 2017.04.01
    18. Clinicopathological features and surgical options for synchronous colorectal cancer. [ MEDICINE ] - 2017.03.01
    19. Anastomotic Recurrence After Curative Resection for Colorectal Cancer. [ WORLD JOURNAL OF SURGERY ] - 2017.01.01
    20. The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy [ Oncotarget ] - 2016.10.18
    21. Factors affecting poor nutritional status after small bowel resection in patients with Crohn disease [ MEDICINE ] - 2016.07.01
    22. Oncologic Safety of Local Excision Compared With Total Mesorectal Excision for ypT0-T1 Rectal Cancer [ MEDICINE ] - 2016.05.01
    23. Surgical Treatment of Crohn Colitis Involving More Than 2 Colonic Segments [ MEDICINE ] - 2016.05.01
    24. Effectiveness of adjuvant radiotherapy after local excision of rectal cancer with deep submucosal invasion: a single-hospital, case-control analysis [ SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES ] - 2015.11.01
    25. The Clinical Features and Predictive Risk Factors for Reoperation in Patients With Perianal Crohn Diseases; A Multi-Center Study of a Korean Inflammatory Bowel Disease Study Group. [ Annals of coloproctology ] - 2015.10.01
    26. Clinical Features and Prognosis of Resectable Primary Colorectal Signet-Ring Cell Carcinoma. [ Intestinal Research ] - 2015.10.01
    27. Role of Adjuvant Chemotherapy in ypT0-2N0 Patients Treated with Preoperative Chemoradiation Therapy and Radical Resection for Rectal Cancer [ INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS ] - 2015.07.01
    28. Long-term results of adipose-derived stem cell therapy for the treatment of Crohn's fistula [ STEM CELLS TRANSLATIONAL MEDICINE ] - 2015.05.01
    29. Surgical outcomes of Korean ulcerative colitis patients with and without colitis-associated cancer [ WORLD JOURNAL OF GASTROENTEROLOGY ] - 2015.03.28
    30. Ratio of metastatic lymph nodes is more important for rectal cancer patients treated with preoperative chemoradiotherapy [ WORLD JOURNAL OF GASTROENTEROLOGY ] - 2015.03.21
    31. Prognostic impact of diagnosing colorectal neuroendocrine carcinoma using the World Health Organization 2010 classification [ SURGERY ] - 2014.04.01
    32. Current issues in locally advanced colorectal cancer treated by preoperative chemoradiotherapy [ WORLD JOURNAL OF GASTROENTEROLOGY ] - 2014.02.28
    33. Clinical implication of additional selective lateral lymph node excision in patients with locally advanced rectal cancer who underwent preoperative chemoradiotherapy [ INTERNATIONAL JOURNAL OF COLORECTAL DISEASE ] - 2013.12.01
    34. Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn's fistula. [ STEM CELLS ] - 2013.11.01
    35. Characteristics and risk factors associated with permanent stomas after sphincter-saving resection for rectal cancer. [ AMERICAN JOURNAL OF SURGERY ] - 2013.10.01
    36. Chronological Improvement in Survival Following Rectal Cancer Surgery: A Large-Scale, Single-Center Study [ WORLD JOURNAL OF SURGERY ] - 2013.07.01
    37. Characteristic phenotypes in korean Crohn's disease patients who underwent intestinal surgery for the treatment [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2013.04.01
    38. The Role of Diverting Stoma After an Ultra-low Anterior Resection for Rectal Cancer. [ 대한대장항문학회지 ] - 2013.04.01
    39. Autologous adipose tissue-derived stem cells for the treatment of Crohn's fistula: a phase I clinical study. [ CELL TRANSPLANTATION ] - 2013.01.01
    40. Oncologic outcome after preoperative chemoradiotherapy in patients with pathologic T0 (ypT0) rectal cancer. [ DISEASES OF THE COLON & RECTUM ] - 2012.10.01
    41. Risk factors for complications after bowel surgery in Korean patients with Crohn's disease. [ 대한외과학회지 ] - 2012.09.01
    42. Risk Factors for Repeat Abdominal Surgery in Korean Patients with Crohn’s Disease: A Multi-Center Study of a Korean Inflammatory Bowel Disease Study Group [ 대한대장항문학회지 ] - 2012.08.01
    43. Clinical Significance of Pre- to Post-Chemoradiotherapy s-CEA Reduction Ratio in Rectal Cancer Patients Treated with Preoperative Chemoradiotherapy and Curative Resection [ ANNALS OF SURGICAL ONCOLOGY ] - 2011.11.01
    44. Effectiveness of Biofeedback Therapy in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surgery [ DISEASES OF THE COLON & RECTUM ] - 2011.09.01
    45. Randomized phase 3 trial comparing preoperative and postoperative chemoradiotherapy with capecitabine for locally advanced rectal cancer [ CANCER ] - 2011.08.15
    46. Mucinous Rectal Cancer: Effectiveness of Preoperative Chemoradiotherapy and Prognosis [ ANNALS OF SURGICAL ONCOLOGY ] - 2011.08.01
    47. Symptomatic Venous Thromboembolism in Asian Colorectal Cancer Surgery Patients [ WORLD JOURNAL OF SURGERY ] - 2011.04.01
    48. Safety and Efficacy of Methylnaltrexone in Shortening the Duration of Postoperative Ileus Following Segmental Colectomy: Results of Two Randomized, Placebo-Controlled Phase 3 Trials. [ DISEASES OF THE COLON & RECTUM ] - 2011.04.01
    49. COMPLICATIONS AFTER SPHINCTER-SAVING RESECTION IN RECTAL CANCER PATIENTS ACCORDING TO WHETHER CHEMORADIOTHERAPY IS PERFORMED BEFORE OR AFTER SURGERY [ INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS ] - 2010.09.01
    50. Intra-abdominal Fistulas in Surgically Treated Crohn's Disease Patients [ WORLD JOURNAL OF SURGERY ] - 2010.08.01
    51. 결장암 위치에 따른 예후 및 재발양상의 비교 [ 대한대장항문학회 ] - 2009.07.23
    52. 궤양성 대장염 환자에서 시행되는 회장낭 수술에 대한 이견 [ 대한대장항문학회지 ] - 2009.06.03
    53. 염증성 장질환에 동반된 악성종양 [ 대한대장항문학회지 ] - 2009.05.27
    54. 수술전 화학방사선치료에 병리학적 완전관해를 보인 직장암환자의 임상병리학적 특징 및 종양학적 결과 [ 대한대장항문학회지 ] - 2008.12.31
    55. 재건대장직장절제술 후 회장낭 실패의 위험 인자 [ 대한대장항문학회 ] - 2008.07.08
    56. Risk factors for lymph node metastasis in submucosal invasive cancer [ WORLD JOURNAL OF SURGERY ] - 2008.06.14
    57. Risk factors and oncologic impact of anastomotic leakage after rectal cancer surgery [ DISEASES OF THE COLON & RECTUM ] - 2008.06.01
    58. 부인과 암수술에 있어서 외과의사의 역할 [ 대한외과학회지 ] - 2008.04.01
    59. 크론병 환자의 수술 후 합병증과 재발 [ 대한대장항문학회 ] - 2008.01.01
    60. 가족성 용종증에서 유건종의 발생양상 [ 대한대장항문학회 ] - 2008.01.01
    61. 건장증진센터에서 진단된 대장암의 특징 [ 대한대장항문학회지 ] - 2007.05.23
    62. 하부 직장암에서 괄약근보존술과 복회음전제술의 장기적 종양학적 결과 [ 대한대장항문학회지 ] - 2007.05.02
    63. Optimal time interval between capecitabine intake and radiotherapy in preoperative chemoradiation for locally advanced rectal cancer [ INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS ] - 2007.02.01
    64. 직장암 수술후 문합부 누출의 위험인자와 예후에 미치는 영향 [ 대한대장항문학회 ] - 2006.12.30
    65. T1 직장암의 치료방법에 따른 종양학적 결과 [ 대한대장항문학회 ] - 2006.10.31
    66. 점막하 침윤 대장암에서 림프절 전이의 위험인자 [ 대한대장항문학회 ] - 2006.08.31
    67. 대장직장절제술 및 회장낭형성숳 후 회장낭염의 발생양상 및 빈도 [ 대한소화기학회 ] - 2005.08.30
    68. 변실금 환자에서 바이오피드백 치료의 효과 [ 대한대장항문학회 ] - 2005.06.30
    69. 정규 대장직장 수술에서 관례적인 비위관 삽입은 필요한가?: 전향적 무작위 연구 [ 대한외과학회 ] - 2005.05.31
    70. 직장암 수술후 발생하는 장유착에 대한 Hyaluronate막의 효과: 전향적 연구 [ 대한대장항문학회 ] - 2005.04.30
    71. 3기 결장암 조직에서 hMLH1과 hMSH2 단백발현의 의의 [ 대한대장항문학회지 ] - 2004.03.01
    72. 진행성 하부 직장암 환자에게 시술된 수술전 방사선 화학요법의 효과 [ 대한대장항문학회지 ] - 2004.03.01
    73. 성인의 Hirschsprung병 [ 대한대장항문학회지 ] - 2003.03.01
    74. 소장 및 대장에서 발생한 원발성 장 림프종 [ 대한외과학회 ] - 2003.03.01
    75. 회장조루술의 합병증 [ 대한대장항문학회지 ] - 2003.03.01
    76. 대장직장 수술 후 장폐색의 임상적 특징 [ 대한대장항문학회지 ] - 2003.03.01

    연구과제 수주실적

    1. 국소진행성직장암 환자의 수술전 화학방사선요법의 치료반응 예측 바이오마커의 개발 - 2017.04.01 ~ 2018.03.31
    2. 수술 전 항암방사선치료 시행 후 임상적으로 관해 혹은 준-관해 직장암 환자에서의 국소절제술의 유효성 평가 - 2017.02.22 ~ 2023.12.31
    3. 수술 전 항암화학요법 시행 후 임상적으로 관해 혹은 준-관해 직장암 환자에서의 국소절제술의 유효성 평가 - 2017.02.22 ~ 2023.12.31
    4. 국소 진행성 직장암 환자에서 방사선반응성지표의 정확도 평가 및 이에 따른 치료전략간의 종양학적 결과 비교연구 - 2015.01.01 ~ 2015.11.30
    5. 국소 진행성 직장암 환자에서 방사선반응성지표의 정확도 평가 및 이에 따른 치료전략간의 종양학적 결과 비교연구 - 2014.12.01 ~ 2014.12.31
    6. 큐피스템®주 시판 후 조사 연구 - 2014.03.06 ~ 2020.06.30
    7. (주)다림티센의 심부체강창상피복재(Collabarrierⓡ)의 회장루 조성술 후 유착방지효과 및 안전성을 비교 평가하기 위한 전향적, 단일기관, 이중눈가림(임상시험 대상자-평가자 눈가림), 무작위 배정 임상시험 - 2013.11.11 ~ 2015.09.30
    8. 크론병으로 인한 누공환자에서 ALLO-ASC-CF(동종 유래 지방 줄기세포)를 용량별 주사한 후 안전성과 효과를 평가하는 제1/2a상 임상시험 - 2013.08.02 ~ 2015.12.31
    9. 큐피스템주를 투여 받은 크론성 누공 환자에 대하여 효과 지속성과 안전성을 장기간 추적 조사하는 후향적 임상연구 - 2013.05.10 ~ 2014.12.31
    10. 위장관 문합술의 보조 용법으로써 EVICEL의 안전성과 효능을 평가하기 위한 단일 맹검 무작위 비교 연구 - 2012.06.04 ~ 2013.12.31
    11. 결장 절제 수술 환자를 대상으로 LD02GIFRO의 장 기능 개선 효과와 안전성을 평가하고,최적 용량을 결정하기 위한 이중눈가림, 다기관, 무작위배정, 위약 대조, 병행 설계,제2상 임상시험 - 2012.02.20 ~ 2013.02.28

    특허/기술이전실적

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