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  • 전상용 교수

    신경외과학

    패스워드가 일치하지 않습니다.

    전공분야

    운동이상증, 척추질환

    소속연구단

    관련/관심분야

        데이터가 없습니다.

    주요논문

    1. GSK-3β and β-Catenin Signaling Pathway is Involved in Myofibroblast Transition of Ligamentum Flavum in Lumbar Spinal Stenosis Patients [ SPINE ] - 2023.10.15
    2. Preventive effects of nano-graphene oxide against Parkinson's disease via reactive oxygen species scavenging and anti-inflammation [ BMB Reports ] - 2023.03.01
    3. Meta-Analysis on the Effect of Hypothermia in Acute Spinal Cord Injury [ Neurospine ] - 2022.09.30
    4. The risk factors of intracerebral hemorrhage in deep brain stimulation: does target matter? [ ACTA NEUROCHIRURGICA ] - 2022.02.28
    5. CRISPR-Cas9 Gene Editing Protects from the A53T-SNCA Overexpression-Induced Pathology of Parkinson's Disease In Vivo [ CRISPR Journal ] - 2022.02.28
    6. Posterior Thoracic Cage Interbody Fusion Offers Solid Bone Fusion with Sagittal Alignment Preservation for De-compression and Fusion Surgery in Lower Thoracic and Thoracolumbar Spine [ JOURNAL OF KOREAN NEUROSURGICAL SOCIETY ] - 2021.11.01
    7. Optimal Ratio of Wnt3a Expression in Human Mesenchymal Stem Cells Promotes Axonal Regeneration in Spinal Cord Injured Rat Model [ JOURNAL OF KOREAN NEUROSURGICAL SOCIETY ] - 2021.09.01
    8. Risk Factors for High-Grade Meningioma in Brain and Spine: Systematic Review and Meta-analysis [ WORLD NEUROSURGERY ] - 2021.07.01
    9. Optogenetic inactivation of the entopeduncular nucleus improves forelimb akinesia in a Parkinson's disease model [ BEHAVIOURAL BRAIN RESEARCH ] - 2020.05.27
    10. Parkinson Disease-Related Pattern of Glucose Metabolism Associated With the Potential for Motor Improvement After Deep Brain Stimulation [ NEUROSURGERY ] - 2020.04.01
    11. Current Status and Future Strategies to Treat Spinal Cord Injury with Adult Stem Cells [ JOURNAL OF KOREAN NEUROSURGICAL SOCIETY ] - 2020.03.01
    12. Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson’s Disease [ CURRENT BIOLOGY ] - 2020.01.20
    13. Clinical outcomes of posterior thoracic cage interbody fusion (PTCIF) to treat trauma and degenerative disease of the thoracic and thoracolumbar junctional spine [ JOURNAL OF CLINICAL NEUROSCIENCE ] - 2019.02.01
    14. The time course of cervical alignment after cervical expansive laminoplasty Determining optimal cut-off preoperative angle for predicting postoperative kyphosis [ MEDICINE ] - 2018.11.21
    15. Practicality of using the figure-of-eight bandage to prevent fatal wound dehiscence after spinal tumor surgery for upper thoracic metastasis [ BRITISH JOURNAL OF NEUROSURGERY ] - 2018.08.01
    16. Analysis of the Risk Factors Associated with Prolonged Intubation or Reintubation after Anterior Cervical Spine Surgery [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2018.04.23
    17. A Novel Animal Model of Parkinson’s Disease Using Optogenetics: Representation of Various Disease Stages by Modulating the Illumination Parameter [ STEREOTACTIC AND FUNCTIONAL NEUROSURGERY ] - 2018.04.01
    18. Relevance of Postoperative Magnetic Resonance Images in Evaluating Epidural Hematoma After Thoracic Fixation Surgery [ WORLD NEUROSURGERY ] - 2017.11.01
    19. An Airway Management Protocol after Anterior Cervical Spine Surgery: Analysis the Results of Risk Factors Associated With Airway Complication. [ SPINE ] - 2017.09.01
    20. Morphological analysis of interbody fusion following posterior lumbar interbody fusion with cages using computed tomography [ MEDICINE ] - 2017.08.01
    21. Is There Additive Therapeutic Effect When GCSF Combined with Adipose-Derived Stem Cell in a Rat Model of Acute Spinal Cord Injury? [ Journal of Korean Neurosurgical Society ] - 2017.07.01
    22. Enhanced axonal regeneration by transplanted Wnt3a-secreting human mesenchymal stem cells in a rat model of spinal cord injury [ ACTA NEUROCHIRURGICA ] - 2017.05.01
    23. Prognostic factor analysis after surgical decompression and stabilization for cervical spinal-cord injury. [ BRITISH JOURNAL OF NEUROSURGERY ] - 2017.04.01
    24. Analysis of equivalent parameters of two spinal cord injury devices: the New York University impactor versus the Infinite Horizon impactor. [ Spine Journal ] - 2016.11.01
    25. Neuralgias of the Head: Occipital Neuralgia [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2016.04.01
    26. Optogenetic Inhibition of the Subthalamic Nucleus Reduces Levodopa-Induced Dyskinesias in a Rat Model of Parkinson’s Disease [ STEREOTACTIC AND FUNCTIONAL NEUROSURGERY ] - 2016.03.11
    27. A Phase III Clinical Trial Showing Limited Efficacy of Autologous Mesenchymal Stem Cell Therapy for Spinal Cord Injury [ NEUROSURGERY ] - 2016.03.01
    28. Surgical Treatment of a Life-Threatening Large Retropharyngeal Hematoma after Minor Trauma : Two Case Reports and a Literature Review. [ Journal of Korean Neurosurgical Society ] - 2015.09.15
    29. Optogenetic inactivation of the subthalamic nucleus improves forelimb akinesia in a rat model of Parkinson disease. [ NEUROSURGERY ] - 2015.05.01
    30. A unilateral open door laminoplasty technique: prospective analysis of the relationship between midline extensor muscle preservation and postoperative neck pain. [ JOURNAL OF CLINICAL NEUROSCIENCE ] - 2015.02.01
    31. Spinal Intramedullary Metastatic Small Cell Lung Cancer Mimicking Ependymoma on Frozen Biopsy During Surgery: A Case Report [ NEUROSURGERY QUARTERLY ] - 2015.02.01
    32. Enhanced Efficacy of Human Brain-Derived Neural Stem Cells by Transplantation of Cell Aggregates in a Rat Model of Parkinson’s Disease [ Journal of Korean Neurosurgical Society ] - 2014.11.30
    33. A Rat Model of Striatonigral Degeneration Generated by Simultaneous Injection of 6-Hydroxydopamine into the Medial Forebrain Bundle and Quinolinic Acid into the Striatum [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2014.11.01
    34. Optogenetic Inactivation of the Subthalamic Nucleus Improves Forelimb Akinesia in a Rat Model of Parkinson's Disease. [ NEUROSURGERY ] - 2014.05.01
    35. Analysis on Bilateral Hindlimb Mapping in Motor Cortex of the Rat by an Intracortical Microstimulation Method [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2014.04.01
    36. The result of S1 double screw fixation in patients not suited for L4 and/or L5 pedicle screw insertion [ ACTA NEUROCHIRURGICA ] - 2014.02.01
    37. Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI [ Neural Regeneration Research ] - 2014.02.01
    38. Pre- and Postoperative Lower Extremity Motor Power and Ambulatory Status of Patients With Spinal Cord Compression Due to a Metastatic Spinal Tumor [ SPINE ] - 2013.06.01
    39. Are human dental papilla-derived stem cell and human brain-derived neural stem cell transplantations suitable for treatment of Parkinson’s disease? [ Neural Regeneration Research ] - 2013.05.01
    40. Enhanced neuroregenerative effects by scaffold for the treatment of a rat spinal cord injury with Wnt3a-secreting fibroblasts [ ACTA NEUROCHIRURGICA ] - 2013.05.01
    41. Long-term Outcomes of 2 Cervical Laminoplasty Methods Midline Splitting Versus Unilateral Single Door [ JOURNAL OF SPINAL DISORDERS TECHNIQUES ] - 2012.12.01
    42. Midline-Splitting Open Door Laminoplasty Using Hydroxyapatite Spacers: Comparison between Two Different Shaped Spacers [ JOURNAL OF KOREAN NEUROSURGICAL SOCIETY ] - 2012.10.01
    43. Long-term Results of Spinal Cord Injury Therapy Using Mesenchymal Stem Cells Derived From BoneMarrow in Humans [ NEUROSURGERY ] - 2012.05.01
    44. Evaluation of a multiple system atrophy model in rats using multitracer microPET [ ACTA NEUROCHIRURGICA ] - 2012.05.01
    45. Efficacy of Decompression and Fixation for Metastatic Spinal Cord Compression : Analysis of Factors Prognostic for Survival and Postoperative Ambulation [ JOURNAL OF KOREAN NEUROSURGICAL SOCIETY ] - 2012.01.01
    46. Therapeutic Efficacy of Wnt3a-Secreting Fibroblast Transplantation in a Rat Model of Parkinson’s Disease [ Journal of Korean Society of Stereotactic and Functional Neurosurgery ] - 2011.09.01
    47. Analysis of hemorrhagic risk factors during deep brain stimulation surgery for movement disorders: comparison of the circumferential paired and multiple electrode insertion methods. [ ACTA NEUROCHIRURGICA ] - 2011.08.01
    48. Axonal regeneration effects of Wnt3a-secreting fibroblast transplantation in spinal cord-injured rats. [ ACTA NEUROCHIRURGICA ] - 2011.05.01
    49. Evaluation of efficacy and safety of fentanyl transdermal patch (Durogesic®D-TRANS) in chronic pain [ ACTA NEUROCHIRURGICA ] - 2011.01.01
    50. 척추 경막외 출혈에 대한 수술적 치료성적 분석 [ 대한외상학회 ] - 2010.12.30
    51. Treatment of Spinal Cord Injury with Bone Marrow-Derived, Cultured Autologous Mesenchymal Stem Cells [ TISSUE ENGINEERING AND REGENERATIVE MEDICINE ] - 2010.10.01
    52. Clinical outcomes of simulataneous bilateral pallidotomy in advaned Parkinson's disease [ 대한신경외과학회지 ] - 2004.03.01
    53. 내경동맥 체부에 발생한 자발성 동맥류의 수술적 치료와 합병증의 예방 [ 대한신경외과학회지 ] - 2002.03.31
    54. 두개강내 상의세포종 환자 30례에 있어서 재발에 영향을 주는 예후 인자 [ 대한신경외과학회지 ] - 2001.12.01
    55. 성인에서 천막상부, 두개엽에 위치한 원발성 교모세포종의 치료에서 종양 절제의 역할 [ 대한신경외과학회지 ] - 2001.12.01
    56. 내시경적 경접형동 접근술에 의한 뇌하수체 종양의 수술 [ 대한신경외과학회지 ] - 2001.05.01
    57. Viewing Wand Navigator를 이용한 원위부 중대뇌 동맥류의 수술적 치료 [ 대한뇌혈관외과학회 ] - 2001.03.01
    58. 측두엽내 공간 점유 병소와 동반된 난치성 간질의 수술적 치료 성적 [ 대한신경외과학회지 ] - 2001.01.01

    연구과제 수주실적

    1. 환자 신경줄기세포를 활용한 척추손상 치료제 개발 - 2024.01.01 ~ 2024.12.31
    2. 환자 신경줄기세포를 활용한 척추손상 치료제 개발 - 2023.04.01 ~ 2023.12.31
    3. 오팔몬정 장기 안전성 빅데이터 연구 - 2021.07.22 ~ 2022.07.31
    4. 퇴행성 요추 추간판으로 인한 만성 요통 환자에서 CordSTEMDD 치료 시 안전성, 내약성 및 유효성 평가를 위한 무작위 배정, 이중 눈가림, 위약 대조, 단회 투여, 제1 2a상, 다기관 임상시험 - 2021.04.01 ~ 2022.06.30
    5. 파킨슨병 렛드 모델에서 담창구의 광유전학적 조절을 통한 치료효과 분석 - 2020.01.01 ~ 2020.12.31
    6. 광자극 기술을 이용한 파킨슨병 치료법 개발 - 2019.01.01 ~ 2019.12.31
    7. 바이러스를 이용한 Wnt3a 분비 중간엽 줄기세포의 개발 - 2018.06.01 ~ 2019.03.31
    8. A53T-α-synuclein 과발현 파킨슨병 동물모델에서 유전자편집기술을 이용한 파킨슨병 치료법개발 (KIST 이창준) - 2018.05.01 ~ 2018.12.31
    9. 파킨슨병 렛드 모델에서 광유전학을 이용한 다리속핵의 억제에 관한 연구 - 2018.01.01 ~ 2018.12.31
    10. 바이러스를 이용한 Wnt3a 분비 중간엽 줄기세포의 개발 - 2017.08.01 ~ 2018.05.31
    11. 바이러스를 이용한 Wnt3a 분비 중간엽 줄기세포 제작 및 전임상적 효율성 평가 - 2017.01.01 ~ 2017.12.31
    12. 바이러스를 이용한 Wnt3a 분비 중간엽 줄기세포의 개발 - 2016.11.08 ~ 2017.07.31
    13. 척수손상 동물 모델에서 Wnt3a 분비 중간엽 줄기세포의 반복주입에 따른 치료효과 분석 - 2016.01.01 ~ 2016.12.31
    14. 백서의 척추 수술 모델을 이용한 Collatamp®의 감염과 출혈에 대한 치료효과 연구 - 2015.11.01 ~ 2017.10.31
    15. 인공 신경 네트워킹 시스템의 전임상적 효율성 평가(6) - 2015.03.01 ~ 2016.02.29
    16. 광유전자-기반 뇌심부자극 기술의 In-vivo 환경에서의 신경생리학적 효율성 및 안정성 평가(6) - 2015.01.01 ~ 2015.09.30
    17. 인공 신경 네트워킹 시스템의 전임상적 효율성 평가(5) - 2014.03.01 ~ 2015.02.28
    18. 광유전자-기반 뇌심부자극 기술의 In-vivo 환경에서의 신경생리학적 효율성 및 안정성 평가(5) - 2014.01.01 ~ 2014.12.31
    19. 광유전자-기반 뇌심부자극 기술의 In-vivo 환경에서의 신경생리학적 효율성 및 안정성 평가(4) - 2013.03.01 ~ 2013.12.31
    20. 인공 신경 네트워킹 시스템의 전임상적 효율성 평가(4) - 2013.03.01 ~ 2014.02.28
    21. 광유전자-기반 뇌심부자극 기술의 In-vivo 환경에서의 신경생리학적 효율성 및 안정성 평가[3] - 2012.03.01 ~ 2012.12.31
    22. 인공 신경 네트워킹 시스템의 전임상적 효율성 평가[3] - 2012.03.01 ~ 2013.02.28
    23. 광유전자-기반 뇌심부자극 기술의 In-vivo 환경에서의 신경생리학적 효율성 및 안정성 평가 - 2011.03.03 ~ 2011.12.31
    24. 인공 신경 네트워킹 시스템의 전임상적 효율성 평가[2] - 2011.03.01 ~ 2012.02.29
    25. 인공 신경 네트워킹 시스템의 전임상적 효율성 평가 - 2010.07.01 ~ 2011.02.28
    26. 광유전자-기반 뇌심부자극 기술의 In-vivo 환경에서의 신경생리학적 효율성 및 안정성 평가 - 2010.03.01 ~ 2010.12.31
    27. 백서의 척수손상후 중간엽 줄기세포치료 효과분석 - 2006.09.01 ~ 2006.12.31

    특허/기술이전실적

    1. 실험용 소동물의 운동측정장치 - 2015.11.20
    2. 두부용 세포치료제 및 약물 주입장치 - 2014.01.22

    국내외 경력

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