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  • 홍상범 교수

    내과학

    패스워드가 일치하지 않습니다.

    전공분야

    호흡부전, 중환자집중치료

    소속연구단

    관련/관심분야

        데이터가 없습니다.

    주요논문

    1. Early Gait Function After Lung Transplantation in Patients With and Without Pretransplant Extracorporeal Membrane Oxygenation Support [ TRANSPLANTATION PROCEEDINGS ] - 2023.04.10
    2. Right Ventricular Assist Device With Extracorporeal Membrane Oxygenation for Bridging Right Ventricular Heart Failure to Lung Transplantation: A Single-Center Case Series and Literature Review [ JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA ] - 2022.06.01
    3. Clinical Features and Outcomes of Severe Pneumonia Caused by Endemic Human Coronavirus in Adults [ AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE ] - 2022.05.01
    4. The Distribution of Multidrug-resistant Microorganisms and Treatment Status of Hospital-acquired Pneumonia/Ventilator-associated Pneumonia in Adult Intensive Care Units: a Prospective Cohort Observational Study [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2021.10.25
    5. A physician-led medical emergency team increases the rate of medical interventions: A multicenter study in Korea [ PLOS ONE ] - 2021.10.07
    6. Rapid Response System Improves Sepsis Bundle Compliances and Survival in Hospital Wards for 10 Years [ JOURNAL OF CLINICAL MEDICINE ] - 2021.09.18
    7. Monocyte distribution width compared with C-reactive protein and procalcitonin for early sepsis detection in the emergency department [ PLOS ONE ] - 2021.04.15
    8. Impact of hospitalization duration before medical emergency team activation: A retrospective cohort study [ PLOS ONE ] - 2021.02.19
    9. The effectiveness of vitamin C for patients with severe viral pneumonia in respiratory failure [ JOURNAL OF THORACIC DISEASE ] - 2021.02.01
    10. Rapid Response System Should Be Enhanced at Non-general Ward Locations: a Retrospective Multicenter Cohort Study in Korea [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2021.01.11
    11. The quick sepsis-related organ failure score has limited value for predicting adverse outcomes in sepsis patients with liver cirrhosis [ KOREAN JOURNAL OF INTERNAL MEDICINE ] - 2020.07.01
    12. Predictive powers of the Modified Early Warning Score and the National Early Warning Score in general ward patients who activated the medical emergency team [ PLOS ONE ] - 2020.05.14
    13. Right ventricular assist device with an oxygenator using extracorporeal membrane oxygenation as a bridge to lung transplantation in a patient with severe respiratory failure and right heart decompensation [ Acute and Critical Care ] - 2020.05.01
    14. Preoperative and intraoperative argatroban as anticoagulant for bridging a patient with heparin-induced thrombocytopaenia to lung transplantation [ EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY ] - 2020.05.01
    15. Improved survival rates in patients with H1N1 acute respiratory failure in Korea between 2009 and 2016. [ PLoS One ] - 2019.10.03
    16. Prone positioning before extracorporeal membrane oxygenation for severe acute respiratory distress syndrome: A retrospective multicenter study [ MEDICINA INTENSIVA ] - 2019.10.01
    17. Serum developmental endothelial locus-1 is associated with severity of sepsis in animals and humans [ SCIENTIFIC REPORTS ] - 2019.09.10
    18. Outcomes of severe human metapneumovirus-associated community-acquired pneumonia in adults [ JOURNAL OF CLINICAL VIROLOGY ] - 2019.08.01
    19. Extended Use of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Retrospective Multicenter Study [ Tuberculosis and Respiratory Diseases(결핵 및 호흡기질환) ] - 2019.07.01
    20. Central Extracorporeal Membrane Oxygenation for Bridging of Right-Sided Heart Failure to Lung Transplantation: A Single-Center Experience and Literature Review [ JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA ] - 2019.07.01
    21. Use of extracorporeal membrane oxygenation in patients with acute high-risk pulmonary embolism: a case series with literature review [ Acute and Critical Care ] - 2019.05.31
    22. Vitamin C alone does not improve treatment outcomes in mechanically ventilated patients with severe sepsis or septic shock: a retrospective cohort study [ JOURNAL OF THORACIC DISEASE ] - 2019.04.01
    23. Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients [ CRITICAL CARE ] - 2019.01.03
    24. Video laryngoscopy versus direct laryngoscopy for first-attempt tracheal intubation in the general ward [ ANNALS OF INTENSIVE CARE ] - 2018.08.13
    25. Lung Transplantation as a Therapeutic Option in Acute Respiratory Distress Syndrome [ TRANSPLANTATION ] - 2018.05.01
    26. Age is major factor for predicting survival in patients with acute respiratory failure on extracorporeal membrane oxygenation: a Korean multicenter study. [ JOURNAL OF THORACIC DISEASE ] - 2018.03.01
    27. The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes [ KOREAN JOURNAL OF INTERNAL MEDICINE ] - 2018.01.01
    28. Humidifier Disinfectant-Associated Lung Injury: Six Years after the Tragic Event [ Tuberculosis and Respiratory Diseases(결핵 및 호흡기질환) ] - 2017.10.01
    29. A risk scoring model based on vital signs and laboratory data predicting transfer to the intensive care unit of patients admitted to gastroenterology wards. [ JOURNAL OF CRITICAL CARE ] - 2017.08.01
    30. Lung function in patients with lung injury due to household chemical inhalation: Post hoc analysis of a prospective nationwide cohort. [ RESPIROLOGY ] - 2017.02.01
    31. Medical emergency team may reduce obstetric intensive care unit admissions. [ JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH ] - 2017.01.01
    32. Glucose-insulin-potassium correlates with hemodynamic improvement in patients with septic myocardial dysfunction [ JOURNAL OF THORACIC DISEASE ] - 2016.12.01
    33. Naringin Decreases TNF-α and HMGB1 Release from LPS-Stimulated Macrophages and Improves Survival in a CLP-Induced Sepsis Mice. [ PLoS One ] - 2016.10.07
    34. Beta-blockers in patients with septic shock: plenty of promise, but no hard evidence yet. [ JOURNAL OF THORACIC DISEASE ] - 2016.09.01
    35. Flow cytometric measurement of respiratory burst activity and surface expression of neutrophils for septic patient prognosis. [ CYTOMETRY PART B-CLINICAL CYTOMETRY ] - 2016.07.01
    36. Lung Transplantation for Chronic Humidifier Disinfectant-Associated Lung Injury. [ 대한중환자의학회지 ] - 2016.05.01
    37. Sepsis and Acute Respiratory Distress Syndrome: Recent Update. [ Tuberculosis and Respiratory Diseases(결핵 및 호흡기질환) ] - 2016.04.01
    38. Comparable Efficacy of Tigecycline versus Colistin Therapy for Multidrug-Resistant and Extensively Drug-Resistant Acinetobacter baumannii Pneumonia in Critically Ill Patients. [ PLoS One ] - 2016.03.02
    39. Immature platelet fraction in septic patients: clinical relevance of immature platelet fraction is limited to the sensitive and accurate discrimination of septic patients from non-septic patients, not to the discrimination of sepsis severity. [ Annals of Laboratory Medicine ] - 2016.01.31
    40. Peramivir is as effective as oral oseltamivir in the treatment of severe seasonal influenza. [ JOURNAL OF MEDICAL VIROLOGY ] - 2015.10.01
    41. Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria. [ The Korean Society of Critical Care Medicine ] - 2015.08.01
    42. A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock. [ The Korean Journal of Internal Medicine ] - 2015.07.01
    43. Modified Early Warning Score Changes Prior to Cardiac Arrest in General Wards. [ PLoS One ] - 2015.06.22
    44. Video laryngoscopy versus direct laryngoscopy for tracheal intubation during in-hospital cardiopulmonary resuscitation. [ RESUSCITATION ] - 2015.04.01
    45. Failure of high-flow nasal cannula therapy may delay intubation and increase mortality. [ INTENSIVE CARE MEDICINE ] - 2015.04.01
    46. Fraction of immature granulocytes reflects severity but not mortality in sepsis. [ SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION ] - 2015.01.01
    47. Impact of serial measurements of lysophosphatidylcholine on 28-day mortality prediction in patients admitted to the intensive care unit with severe sepsis or septic shock. [ JOURNAL OF CRITICAL CARE ] - 2014.10.01
    48. A cluster of lung injury associated with home humidifier use: clinical, radiological and pathological description of a new syndrome. [ THORAX ] - 2014.08.01
    49. Recovery from Acute Respiratory Distress Syndrome with Long-Run Extracorporeal Membrane Oxygenation [ 대한중환자의학회지 ] - 2014.08.01
    50. Usefulness of Cellular Analysis of Bronchoalveolar Lavage Fluid for Predicting the Etiology of Pneumonia in Critically Ill Patients [ PLoS One ] - 2014.05.13
    51. Activation of a medical emergency team using an electronic medical recording-based screening system [ CRITICAL CARE MEDICINE ] - 2014.04.01
    52. Intratracheal administration of umbilical cord blood-derived mesenchymal stem cells in a patient with acute respiratory distress syndrome. [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2014.03.01
    53. Does Medical Emergency Team intervention reduce the prevalence of emergency endotracheal intubation complications? [ YONSEI MEDICAL JOURNAL ] - 2014.01.01
    54. Low-tidal volume mechanical ventilation in patients with acute respiratory distress syndrome caused by pandemic influenza A/H1N1 infection. [ JOURNAL OF CRITICAL CARE ] - 2013.08.01
    55. Epidemiological analysis of critically ill adult patients with pandemic influenza A(H1N1) in South Korea [ EPIDEMIOLOGY AND INFECTION ] - 2013.05.01
    56. A Comparison of Acute Kidney Injury Classifications in Patients With Severe Sepsis and Septic Shock [ AMERICAN JOURNAL OF THE MEDICAL SCIENCES ] - 2012.11.01
    57. Clinical significance of enzymatic lysophosphatidylcholine (LPC) assay data in patients with sepsis [ EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES ] - 2012.08.01
    58. A COMPARISON OF THE TIME FROM SEPSIS TO INCEPTION OF CONTINUOUS RENAL REPLACEMENT THERAPY VERSUS RIFLE CRITERIA IN PATIENTS WITH SEPTIC ACUTE KIDNEY INJURY [ SHOCK ] - 2012.07.01
    59. 침습적 기계환기로도 호전이 되지 않는 치료불응성 천식 환자에서 Interventional Lung Assist를 적용한 1예 [ 대한중환자의학회지 ] - 2012.05.01
    60. Physiologic Effect and Safety of the Pumpless Extracorporeal Interventional Lung Assist System in Patients With Acute Respiratory FailureuA Pilot Study [ ARTIFICIAL ORGANS ] - 2012.04.01
    61. Fatal pandemic influenza A/H1N1 infection complicated by probable invasive pulmonary aspergillosis [ MYCOSES ] - 2012.03.01
    62. Analysis of progression in risk, injury, failure, loss, and end-stage renal disease classification on outcome in patients with severe sepsis and septic shock [ JOURNAL OF CRITICAL CARE ] - 2012.02.01
    63. 성인 호흡곤란 증후군에 있어 체외막 산소화 장치를 이용한 치료 [ 대한결핵및호흡기학회 ] - 2012.01.01
    64. Triple-Combination Antiviral Drug for Pandemic H1N1 Influenza Virus Infection in Critically Ill Patients on Mechanical Ventilation [ ANTIMICROBIAL AGENTS AND CHEMOTHERAPY ] - 2011.12.01
    65. Low-dose hydrocortisone treatment for patients with septic shock: A pilot study comparing 3 days with 7 days [ RESPIROLOGY ] - 2011.10.01
    66. Analysis of systemic corticosteroid usage and survival in patients requiring mechanical ventilation for severe community-acquired pneumonia [ JOURNAL OF INFECTION AND CHEMOTHERAPY ] - 2011.08.01
    67. Usefulness of Quantitative Endotracheal Aspirate Cultures in Intensive Care Unit Patients with Suspected Pneumonia [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2011.04.01
    68. 급성 기도폐쇄 환자에서 일시적인 체외막산소화장치를 이용한 성공적 기도확보 3예 [ 대한중환자의학회지 ] - 2011.03.31
    69. 혈청 프로칼시토닌(serum procalcitonin) 측정을 통한 패혈증 진단 및 중증도 평가의 유용성 [ Tuberculosis and Respiratory Diseases(결핵 및 호흡기질환) ] - 2011.02.01
    70. Critically Ill Patients with Pandemic Influenza A/H1N1 2009 at a Medical Center in Korea [ Tuberculosis and Respiratory Diseases ] - 2011.02.01
    71. Relationship between the MIC of vancomycin and clinical outcome in patients with MRSA nosocomial pneumonia [ INTENSIVE CARE MEDICINE ] - 2011.01.21
    72. 급성 호흡부전 환자에서 Pumpless Extracorporeal Interventional Lung Assist의 생리학적 효과 및 안전성 [ 대한중환자의학회지 ] - 2010.12.01
    73. 원저 : 대한민국 신종인플루엔자 관련 사망자의 기저질환에 따른 역학적 특성 [ 대한중환자의학회지 ] - 2010.06.01
    74. 국내 중환자실에서 72시간 이상 인공호흡기 치료를 받는 환자들의 진정제, 진통제 및 근이완제 사용 실태에 대한 전향적 다 기관 공동 조사연구 [ 대한중환자의학회 ] - 2009.12.01
    75. Radiologic and Clinical Outcomes with Special Reference to Tumor Involvement Pattern after Stent Placement for Malignant Bronchial Obstructions [ ACTA RADIOLOGICA ] - 2009.11.01
    76. 폐 침윤을 동반한 급성 중증 환자의 기관지 폐포 세척액에서 측정한 Pre-B-Cell Colony-Enhancing Factor의 임상적 유용성 [ 결핵 및 호흡기질환 ] - 2009.11.01
    77. Characteristics of mechanical ventilation employed in intensive care units: a multicenter survey of hospitals. [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2008.12.23
    78. A multicenter Survey of Hospitals. [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2008.12.01
    79. Diagnostic Utility of the Soluble Triggering Receptor Expressed on Myeloid Cells-1 in BAL Fluid from Patients with Bilateral Lung Infiltrates [ CRITICAL CARE ] - 2008.01.19
    80. 급성호흡곤란증후군 환자에서 Soluble Triggering Receptor Expressed on Myeloid Cells-1의 예후인자로서의 유용성 [ 결핵 및 호흡기질환 ] - 2008.01.01
    81. Essential Role of Pre–B-Cell Colony Enhancing Factor in Ventilator-induced Lung Injury [ AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE ] - 2008.01.01
    82. 기관과 기관지내 다발성 점막 병변을 동반한 Churg-Strauss 증후군 1예 [ 결핵 및 호흡기질환 ] - 2008.01.01
    83. 급성폐손상에서 기능적 유전체학의 적용 [ 결핵 및 호흡기질환 ] - 2007.11.09
    84. 한 대학병원 내과계중환자실에서 장기간 기계 환기를 받은 환자들의 3년 예후 [ 결핵 및 호흡기질환 ] - 2007.03.09
    85. Skin necrosis after low-dose vasopressin infusion through central venous catheter for septic shock. [ The Korean Journal of Internal Medicine ] - 2006.12.29
    86. 한 내과계 중환자실에서 치료하였던 중증 알코올성 케톤산증 환자들의 임상적 특성 [ 대한결핵및호흡기학회 ] - 2006.05.31
    87. 국내 한 3차 병원 중환자실에 입원한 중증지역획득폐렴 환자의 원인 미생물과 경험적 항균제 치료 성적의 고찰 [ 결핵 및 호흡기질환 ] - 2005.11.01
    88. 쇽 혹은 우심실부전을 보이는 중증 폐혈전색전증에서 혈전용해요법과 항응고요법의 효과 [ 결핵 및 호흡기질환 ] - 2005.11.01
    89. 내과계 중환자실 환자에서 Chlorhexidine-silver Sulfadiazine Coated Catheter의 중심정맥관 감염에 대한 연구 [ 결핵 및 호흡기질환 ] - 2005.10.01
    90. HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome에 합병된 미만성 폐포출혈 1예 [ 결핵 및 호흡기질환 ] - 2005.09.01
    91. Induced hypothermia as a new approach to lung rest for the acutely injured lung [ CRITICAL CARE MEDICINE ] - 2005.09.01
    92. 객담에서 Multi-drug Resistant Acinetobactor baumannii가 동정된 중환자실 환자에서 Clinical Pulmonary infections score의 임상적 유용성 [ 결핵 및 호흡기질환 ] - 2003.04.01
    93. 심질환 병력이 없었던 중환자에서 B-type Natriuretic Peptide검사의 유용성 [ 결핵 및 호흡기질환 ] - 2003.04.01

    연구과제 수주실적

    1. 저박사주의 시판 후 조사를 통한 안전성 및 유효성 평가 - 2022.05.11 ~ 2023.04.06
    2. 패혈성 쇼크 환자에서 폴리에틸렌이민 코팅 필터(oXiris(TM))를 이용한 혈액관류요법의 효과 다기관 무작위배정연구 - 2021.10.27 ~ 2023.09.30
    3. 일반병동 입원 환자를 대상으로 인공지능 기반 심정지 예측 소프트웨어 VUNO Med - DeepCARS(내장 기능 검사용 기기)의 심정지 예측에 대한 유효성을 평가하기 위한 단일기관, 코호트 내 환자-대조군, 후향적, 확증 임상시험 - 2020.08.06 ~ 2021.02.28
    4. 고위험 환자군의 조기 발견 및 선제적 대응을 위한 한국형 조기경고점수체계 다(多) 의료기관 확산 모델 개발 및 실증 연구 - 2020.01.01 ~ 2021.06.30
    5. 패혈증 조기 진단 바이오마커 및 치료제 발굴을 위한 실험 연구 - 2019.08.28 ~ 2022.06.30
    6. 고위험 환자군의 조기 발견 및 선제적 대응을 위한 한국형 조기경고점수체계 다(多) 의료기관 확산 모델 개발 및 실증 연구 - 2019.01.01 ~ 2019.12.31
    7. 병원-획득 세균성 폐렴이나 인공호흡기-관련 세균성 폐렴 환자를 대상으로 Imipenem/ Cilastatin/Relebactam (MK-7655A)의 안전성, 내약성, 유효성을 P - 2018.10.09 ~ 2019.05.31
    8. 고위험 환자군의 조기 발견 및 선제적 대응을 위한 한국형 조기경고점수체계 다(多) 의료기관 확산 모델 개발 및 실증 연구 - 2018.05.30 ~ 2018.12.31
    9. 중증 급성호흡부전 환자에서 체외순환막형산화요법(ECMO)의 임상적 유용성 평가 및 국내 적응증 개발 - 2016.11.01 ~ 2017.10.31
    10. 고위험군 환자의 조기 발견 및 선제적 대응을 위한 시스템 구축 - 2016.08.01 ~ 2017.07.31
    11. 중증 급성호흡부전 환자에서 체외순환막형산화요법(ECMO)의 임상적 유용성 평가 및 국내 적응증 개발 - 2016.05.11 ~ 2016.10.31
    12. 고위험군 환자의 조기 발견 및 선제적 대응을 위한 시스템 구축 - 2015.08.01 ~ 2016.07.31
    13. 레가론을 이용한 패혈증에 유효한 신규물질의 발굴 - 2015.05.01 ~ 2016.12.31
    14. 응고장애가 있는 중증 패혈증 환자를 대상으로 ART-123의 안전성 및 유효성을 평가하기 위한 무작위배정, 이중 눈가림, 위약 대조, 제 3상 임상시험 - 2015.01.12 ~ 2018.04.30
    15. 기계 호흡 상태의 그람 양성 원내 폐렴에서 TR-701 FA와 리네졸리드를 비교하는 3상 무작위 배정 이중 맹검 연구 - 2014.09.05 ~ 2018.07.14
    16. 인공호흡기에 의한 원내 폐렴을 가진 성인 환자에서 메로페넴(MEROPENEM)과 비교하여 세프톨로잔(CEFTOLOZANE)/타조박탐(TAZOBACTAM) 정맥 주사의 안전성 및 유효성을 평가하기 위한 전향적, 무작위배정, 이중-눈가림, 다기관, 제 3상 임상시험 - 2014.09.03 ~ 2018.04.07
    17. 지역사회 획득 세균성 폐렴 성인 환자 치료에서 정맥 투여에서 경구 투여로 전환되는 목시플록사신 요법과 비교하여 정맥 투여에서 경구 투여로 전환되는 솔리스로마이신(CEM-101) 요법의 유효성 및 안전성을 평가하는 무작위배정, 이중 눈가림, 다기관 연구 - 2014.01.27 ~ 2015.07.15
    18. 중증 호흡 부전 환자에서의 중간엽 줄기 세포의 치료 효과와 안전성을 위한 예비 연구(pilot study) - 2013.05.14 ~ 2015.02.01

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    국내외 경력

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