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  • 이철환 교수

    내과학

    패스워드가 일치하지 않습니다.

    전공분야

    관상동맥질환, 관상동맥중재술

    소속연구단

    관련/관심분야

        데이터가 없습니다.

    주요논문

    1. Quantitative coronary angiography versus intravascular ultrasound guidance for drug-eluting stent implantation (GUIDE-DES): study protocol for a randomised controlled non-inferiority trial [ BMJ OPEN ] - 2022.01.13
    2. Functional Angioplasty: Definitions, Historical Overview, and Future Perspectives [ Korean Circulation Journal ] - 2022.01.01
    3. Comparison of empagliflozin and sitagliptin therapy on myocardial perfusion reserve in diabetic patients with coronary artery disease [ NUCLEAR MEDICINE COMMUNICATIONS ] - 2021.09.01
    4. Effects of Fixed-dose Combination of Low-intensity Rosuvastatin and Ezetimibe Versus Moderate- intensity Rosuvastatin Monotherapy on Lipid Profiles in Patients With Hypercholesterolemia: A Randomized, Double-blind, Multicenter, Phase III Study [ CLINICAL THERAPEUTICS ] - 2021.08.21
    5. Intracranial Bleeding After Percutaneous Coronary Intervention: Time-Dependent Incidence, Predictors, and Impact on Mortality [ JOURNAL OF THE AMERICAN HEART ASSOCIATION ] - 2021.08.03
    6. Statin/ezetimibe combination therapy vs statin monotherapy for carotid atherosclerotic plaque inflammation [ MEDICINE ] - 2021.03.12
    7. Comparison of High-Dose Rosuvastatin Versus Low-Dose Rosuvastatin Plus Ezetimibe on Carotid Atherosclerotic Plaque Inflammation in Patients with Acute Coronary Syndrome [ JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH ] - 2020.12.01
    8. Meta-Analysis Comparing the Risk of Myocardial Infarction Following Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention in Patients With Multivessel or Left Main Coronary Artery Disease [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2019.09.15
    9. Effects of ezetimibe/simvastatin 10/10 mg versus Rosuvastatin 10 mg on carotid atherosclerotic plaque inflammation [ BMC CARDIOVASCULAR DISORDERS ] - 2019.08.19
    10. Comparison of Fimasartan and Amlodipine Therapy on Carotid Atherosclerotic Plaque Inflammation [ CLINICAL CARDIOLOGY ] - 2019.02.01
    11. Sex differences in left main coronary artery stenting: Different characteristics but similar outcomes for women compared with men [ INTERNATIONAL JOURNAL OF CARDIOLOGY ] - 2018.02.15
    12. Comparison of a Simple Angiographic Approach With a Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery Score-Based Approach for Left Main Coronary Artery Stenting: A Pooled Analysis of Serial PRECOMBAT (Premier of Rando [ Circulation-Cardiovascular Interventions ] - 2018.01.01
    13. Impact of left main coronary artery disease on long-term mortality in patients undergoing drug-eluting stent implantation [ CLINICAL RESEARCH IN CARDIOLOGY ] - 2017.12.01
    14. Long-term outcomes of bypass grafting versus drug-eluting stenting for left main coronary artery disease: Results from the IRIS-MAIN registry [ AMERICAN HEART JOURNAL ] - 2017.11.01
    15. Mortality of patients with previous stroke undergoing drug-eluting stent implantation [ CORONARY ARTERY DISEASE ] - 2017.11.01
    16. Stent length and outcomes after drug-eluting stent placement: time to redefine long lesions [ CORONARY ARTERY DISEASE ] - 2017.09.01
    17. Predictors of long-term outcomes after bypass grafting versus drug-eluting stent implantation for left main or multivessel coronary artery disease [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2017.08.01
    18. Comparison of Outcome of Coronary Artery Bypass Grafting Versus Drug-Eluting Stent Implantation for Non-ST-Elevation Acute Coronary Syndrome [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2017.08.01
    19. Comparison of Stenting Versus Bypass Surgery According to the Completeness of Revascularization in Severe Coronary Artery Disease Patient-Level Pooled Analysis of the SYNTAX, PRECOMBAT, and BEST Trials [ JACC-CARDIOVASCULAR INTERVENTIONS ] - 2017.07.24
    20. Comparison of Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stent Implantation in Patients With Severe Left Ventricular Dysfunction [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2017.07.01
    21. Coronary Artery Bypass Grafting vs. Drug-Eluting Stent Implantation for Multivessel Disease in Patients with Chronic Kidney Disease [ KOREAN CIRCULATION JOURNAL ] - 2017.05.01
    22. Coronary artery bypass graft surgery versus drug-eluting stent implantation for high-surgical-risk patients with left main or multivessel coronary artery disease [ EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY ] - 2017.05.01
    23. Outcomes of Coronary Artery Bypass Graft Surgery Versus Drug-Eluting Stents in Older Adults. [ JOURNAL OF THE AMERICAN GERIATRICS SOCIETY ] - 2017.03.01
    24. Impact of Multivessel Coronary Artery Disease With Versus Without Left Main Coronary Artery Disease on Long-Term Mortality After Coronary Bypass Grafting Versus Drug-Eluting Stent Implantation. [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2017.01.15
    25. Reply: Long-Term Mortality After Coronary Revascularization in Nondiabetic Patients With Multivessel Disease. [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2017.01.01
    26. Coronary Artery Bypass Surgery Versus Drug-Eluting Stent Implantation for Left Main or Multivessel Coronary Artery Disease: A Meta-Analysis of Individual Patient Data. [ JACC-Cardiovascular Interventions ] - 2016.12.26
    27. Similar Impact of Clopidogrel or Ticagrelor on Carotid Atherosclerotic Plaque Inflammation. [ CLINICAL CARDIOLOGY ] - 2016.11.01
    28. Long-Term Mortality After Coronary Revascularization in Nondiabetic Patients With Multivessel Disease. [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2016.07.05
    29. Coronary Artery Bypass Grafting Versus Drug-Eluting Stents Implantation for Previous Myocardial Infarction. [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2016.07.01
    30. A Simple, Effective, and Durable Treatment Choice for Left Main Coronary Artery Disease: Stents or Surgery? [ JACC-Cardiovascular Interventions ] - 2016.06.13
    31. Drug-eluting balloon: early enthusiasm being tempered by growing uncertainty [ CORONARY ARTERY DISEASE ] - 2016.03.01
    32. Temporal patterns of drug-eluting stent failure and its relationship with clinical outcomes [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2015.03.01
    33. Dual antiplatelet therapy for coronary artery disease [ CIRCULATION JOURNAL ] - 2015.01.23
    34. Edge dissection of calcified plaque as a possible mechanism for acute coronary syndrome [ JOURNAL OF THROMBOSIS AND THROMBOLYSIS ] - 2014.11.01
    35. Long-Term (8 Year) Outcomes and Predictors of Major Adverse Cardiac Events after Full Metal Jacket Drug-Eluting Stent Implantation [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2014.09.01
    36. Drug-eluting stents for ST-elevation myocardial infarction: ready for prime time? [ CORONARY ARTERY DISEASE ] - 2014.08.01
    37. Differences in intravascular ultrasound and histological findings in culprit coronary plaques between ST-segment elevation myocardial infarction and stable angina [ JOURNAL OF THROMBOSIS AND THROMBOLYSIS ] - 2014.05.01
    38. Optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial. [ CIRCULATION ] - 2014.01.21
    39. Expression of stanniocalcin-1 in culprit coronary plaques of patients with acute myocardial infarction or stable angina [ JOURNAL OF CLINICAL PATHOLOGY ] - 2013.09.15
    40. Comparison of Intravascular Ultrasound and Histological Findings in Culprit Coronary Plaques Between ST-Segment Elevation and Non ST-Segment Elevation Myocardial Infarction [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2013.07.01
    41. Macrophage Heterogeneity of Culprit Coronary Plaques in Patients with Acute Myocardial Infarction or Stable Angina. [ AMERICAN JOURNAL OF CLINICAL PATHOLOGY ] - 2013.03.15
    42. Comparison of Differential Expression of P2Y(12) Receptor in Culprit Coronary Plaques in Patients With Acute Myocardial Infarction Versus Stable Angina Pectoris. [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2011.09.15
    43. Comparison of ruptured coronary plaques in patients with unstable and stable clinical presentation [ JOURNAL OF THROMBOSIS AND THROMBOLYSIS ] - 2011.08.01
    44. Comparison of ADAMTS-1,-4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina [ JOURNAL OF CLINICAL PATHOLOGY ] - 2011.05.01
    45. Expression of HMG-CoA reductase in human coronary atherosclerotic plaques and relationship to plaque destabilisation [ HEART ] - 2011.05.01
    46. Comparison of Dual Drug-Eluting Cilotax Stent and Paclitaxel-Eluting Taxus Liberte Stent in Native Coronary Artery Lesions [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2011.04.01
    47. Comparison of the efficacy and safety of zotarolimus-, sirolimus-, and paclitaxel-eluting stents in patients with ST-elevation myocardial infarction [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2009.11.15
    48. A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus 2-year clinical outcomes of the DES-DIABETES trial. [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2009.03.03
    49. Long-term clinical outcomes after sirolimus-eluting stent implantation for treatment of restenosis within bare-metal versus drug-eluting stents [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2008.03.01
    50. Tissue plasminogen activator on admission is an important predictor of 30-day mortality in patients with acute myocardial infarction undergoing primary angioplasty [ ATHEROSCLEROSIS ] - 2008.01.01
    51. Sirolimus-eluting stent implantation for treatment of proximal left anterior descending coronary artery lesions: Long-term outcome and predictors of adverse cardiac events [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2007.09.01
    52. Factors predictive of cardiac events and restenosis after sirolimus-eluting stent implantation in small coronary arteries [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2007.05.01
    53. Incidence and predictors of recurrent restenosis following implantation of drug-eluting stents for in-stent restenosis [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2007.01.31
    54. Predictors of Restenosis after Placement of Drug-Eluting Stents in One or More Coronary Arteries [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2006.02.15
    55. Temporal Patterns of Gene Expression Following Acute Hindimb Ischemia in Mice: Insights into the Genomic Program for Collateral Development [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2004.03.01
    56. Effect of abciximab on myocardial salvage in patients with acute myocardial infarction undergoing primary angioplasty [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2002.12.01
    57. Influence of coronary collateral flow on restenosis following primary angioplasty for acute myocardial infarction [ CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS ] - 2002.04.01
    58. Determinants and prognostic implications of terminal QRS complex distortion in patients treated with primary angioplasty for acute myocardial infarction [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2001.08.01
    59. Prognostic Significance of Cerebral Metabolic Abnormalities in Patients with Congestive Heart Failure [ CIRCULATION ] - 2001.06.01
    60. Determinants and Prognostic Significance of Spontaneous Coronary Recanalization in Acute Myocardial Infarction [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2001.04.15

    연구과제 수주실적

    1. 원발성 고콜레스테롤혈증 환자를 대상으로 AD221과 AD221A의 유효성과 안전성을 평가하기 위한 무작위배정, 이중눈가림,활성 대조, 다기관 제3상 임상시험 - 2021.12.06 ~ 2022.12.31
    2. 원발성 고콜레스테롤혈증 환자를 대상으로 AD220과 AD220A의 유효성과 안전성을 평가하기 위한 무작위배정, 이중눈가림, 활성대조, 다기관 제 3상 임상시험 - 2021.04.05 ~ 2022.06.30
    3. 원발성 고콜레스테롤혈증 환자를 대상으로 HGP1910 및 HCP1903의 유효성 및 안전성을 평가하기 위한 무작위배정, 양측눈가림, 다기관, 제3상 임상시험 - 2020.04.20 ~ 2022.03.30
    4. 고혈압과 이상지질혈증을 동반한 환자에서 DWJ1451 의 유효성과 안전성을 평가하기 위한 다기관, 무작위배정, 양측눈가림, 3 상 임상시험 - 2019.11.20 ~ 2022.02.28
    5. 과거 심근 경색이나 뇌졸중이 없는 심혈관계 고위험 시험대상자에서 주요 심혈관 사건에 대한 에볼로쿠맙의 영향을 평가하기 위한 이중 눈가림, 무작위배정, 위약 대조, 다기관 시험 - 2019.10.28 ~ 2024.05.31
    6. 안정형관상동맥질환이 있는 당뇨전단계 환자에서 심근관류예비력에 미치는 다파글리플로진의 효과 - 2019.10.28 ~ 2023.02.28
    7. 안정형관상동맥질환 환자에서 관상동맥동맥경화반의 진행에 미치는 고용량스타틴 대비 저용량스타틴과 에제티미브 복합제의 효과비교 - 2019.07.25 ~ 2025.09.30
    8. XATOA-Xarelto + 아세틸살리실산: 죽상동맥경화증 환자에서의 치료 패턴 및 결과. 비중재 연구. - 2019.01.22 ~ 2022.01.31
    9. XATOA-Xarelto + 아세틸살리실산: 죽상동맥경화증 환자에서의 치료 패턴 및 결과. 비중재 연구. - 2018.12.20 ~ 2022.01.31
    10. 한국에서 레파타주(에볼로쿠맙) 사용성적조사 - 2018.09.13 ~ 2023.04.12
    11. 급성관동맥증후군 환자에서 경동맥의 동맥경화반 염증에 미치는 고용량 로수바스타틴 대비 저용량 로수바스타틴과 에제티미브 복합제의 효과 무작위비교연구 - 2017.02.09 ~ 2020.01.31
    12. 동적 심근 단일광자 단층촬영 (Dynamic myocardial single-photon emission computed tomography (SPECT))로 평가한 심근 관류 예비능 (global myocardial perfusion reserve)에 대한 엠파글리플로진 (Empagliflozin)과 시타글립틴 (Sitagliptin)의 치료 효과 비교 - 2016.10.26 ~ 2018.09.30
    13. 고혈압과 고지혈증을 동반한 환자에서 Nebivolol/Rosuvastatin 투여군의 유효성과 안전성을 평가하기 위한 다기관, 무작위배정, 양측눈가림, 제 3상 임상시험 - 2016.09.12 ~ 2018.05.31
    14. 급성 관상동맥 증후군이 있거나 경피적 관상동맥 중재술을 받는 심방세동 환자에서 아픽사반 대 비타민 K 길항제와 아스피린 대 아스피린 위약의 안전성을 평가하는 공개, 2 x 2 요인, 무작위 배정 비교 임상시험 - 2016.05.23 ~ 2017.11.30
    15. 협심증으로 약물스텐트를 삽입한 환자에서 단기간 이중항혈소판 치료 후 장기간 클로피도그렐 단독 유지요법의 임상효과 (STAMP-DES 연구) - 2015.03.18 ~ 2019.06.30
    16. 경동맥질환의 동맥경화반 염증에 미치는 피마살탄과 암로디핀의 효과 비교 - 2015.02.25 ~ 2018.01.31
    17. 급성관동맥증후군의 발병기전과 이를 유발하는 새로운 표적물질의 발굴 - 2015.01.01 ~ 2015.11.30
    18. 급성관동맥증후군의 발병기전과 이를 유발하는 새로운 표적물질의 발굴 - 2014.12.01 ~ 2014.12.31
    19. 스타틴의 동맥경화증 진행 조기예방효과 - 2014.02.03 ~ 2017.07.31
    20. 고위험 시험대상자의 주요 심혈관 사건 발생을 감소시키기 위해 사용된 PF-04950615의 유효성, 안전성 및 내약성을 평가하는 제3상, 다기관, 이중 눈가림, 무작위 배정, 위약 대조, 평행군 시험 (B1481022) - 2014.01.28 ~ 2017.08.28
    21. 고위험 시험대상자의 주요 심혈관 사건 발생을 감소시키기 위해 사용된 PF04950615의 유효성, 안전성 및 내약성을 평가하는 제3상, 다기관, 이중 눈가림, 무작위 배정, 위약 대조, 평행군 시험 (B1481038) - 2014.01.27 ~ 2016.11.09
    22. FDG PET/CT으로 평가한 경동맥과 대동맥의 동맥경화반염증에 대한 클로피도그렐과 티카그렐러의 치료효과비교 - 2013.07.19 ~ 2017.06.30
    23. 당뇨병을 동반한 관상동맥 질환이 있는 환자에서 이중약물 용출성 실로탁스 스텐트와 에베로리무스 용출성 스텐트 간의 비교에 대한 무작위배정, 다기관 임상연구 - 2013.04.01 ~ 2015.03.31
    24. 당뇨병을 동반한 관상동맥 질환이 있는 환자에서 이중약물 용출성 실로탁스 스텐트와 에베로리무스 용출성 스텐트 간의 비교에 대한 무작위배정, 다기관 임상연구 - 2012.05.01 ~ 2013.03.31
    25. 동맥경화반의 파열기전규명과 취약성동맥경화반의 특이적인 새로운 영상진단법 및 유전자 적중 동물모델의 개발 - 2012.04.01 ~ 2013.03.31
    26. 허혈성심질환 임상연구센터(세부) - 2012.04.01 ~ 2013.03.31
    27. 약물방출조절형 생체적합성 고분자를 이용한 다층코딩 스텐트 시스템의 효용성 및 안전성 평가 - 2008.01.07 ~ 2009.11.06
    28. 급성심근경색증과 불안정형협심증의 동맥경화반 파열부위에서 발현되는 유전자 차이의 비교분석 - 2007.07.07 ~ 2009.12.31
    29. 돼지의 관상동맥 재협착모델을 사용하여 새로이 개발된 국산 약물 스텐트(Drug-Eluting Stent)의 효능평가 - 2006.01.01 ~ 2007.12.31
    30. 관상동맥의 동맥결화반에 대한 atorbastatin과 rosubaxtatin 의 치료효과: 혈관 내 초음파를 사용한 전향적 무작위 비교연구 - 2005.12.01 ~ 2009.06.30
    31. 일차적 관동맥성형술을 시행받은 급성심근경색 환자에서 내원시 Tissue Plasminogen Activator 측정의 임상적 유용성 - 2005.09.01 ~ 2006.08.31
    32. 급성관동맥증후군을 유발하는 동맥경화반의 파열과 관련된 새로운 유전자의 발급 - 2004.10.01 ~ 2006.09.30
    33. 당뇨병 환자에서 그물망 시술후 발생하는 신생내막형성에 대한 Rosiglitazone의 효과 : 혈관내초음파 추적검사 - 2004.07.15 ~ 2007.07.15

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