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  • 송재관 교수

    내과학

    패스워드가 일치하지 않습니다.

    전공분야

    심초음파, 판막증, 대동맥질환

    소속연구단

    관련/관심분야

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    주요논문

    1. Autotaxin inhibition attenuates the aortic valve calcifcation by suppressing infammation-driven fbro-calcifc remodeling of valvular interstitial cells [ BMC Medicine ] - 2024.03.14
    2. Effect of race on pressure recovery adjustment for prevention of aortic stenosis grading discordance [ HEART ] - 2023.09.28
    3. Bicuspid aortic valve: evolving knowledge and new questions [ HEART ] - 2022.12.13
    4. Percutaneous coronary intervention in patients with documented coronary vasospasm during long-term follow-up [ HEART ] - 2022.07.27
    5. Validation of aortic valve calcium quantification thresholds measured by computed tomography in Asian patients with calcific aortic stenosis [ EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING ] - 2022.04.18
    6. Different Clinical Features between Definite and Possible Takotsubo Syndrome in a Tertiary Referral Hospital [ CARDIOLOGY ] - 2022.04.01
    7. Evogliptin Suppresses Calcific Aortic Valve Disease by Attenuating Inflammation, Fibrosis, and Calcification [ CELLS ] - 2021.01.01
    8. Dipeptidyl peptidase-4 inhibition to prevent progression of calcific aortic stenosis [ HEART ] - 2020.12.01
    9. Diagnostic and Prognostic Value of Ergonovine Echocardiography for Noninvasive Diagnosis of Coronary Vasospasm [ JACC-CARDIOVASCULAR IMAGING ] - 2020.09.01
    10. Atrial Septal Aneurysm, Shunt Size, and Recurrent Stroke Risk in Patients With Patent Foramen Ovale [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2020.05.12
    11. Clinical Usefulness of Pressure Recovery Adjustment in Patients with Predominantly Severe Aortic Stenosis: Asian Valve Registry Data [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2020.03.01
    12. Clinical Situations Associated with Inappropriately Large Regurgitant Volumes in the Assessment of Mitral Regurgitation Severity Using the Proximal Flow Convergence Method in Patients with Chordae Rupture [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2020.01.01
    13. Differential clinical features and long-term prognosis of acute aortic syndrome according to disease entity [ EUROPEAN HEART JOURNAL ] - 2019.08.21
    14. Time-dependent reversal of significant intrapulmonary shunt after liver transplantation [ KOREAN JOURNAL OF INTERNAL MEDICINE ] - 2019.05.01
    15. Sick Sinus Syndrome After the Maze Procedure Performed Concomitantly With Mitral Valve Surgery [ JOURNAL OF THE AMERICAN HEART ASSOCIATION ] - 2018.10.02
    16. Variable Hemodynamic Responses during Diastolic Stress Echocardiography in Patients Who Have Relaxation Abnormality with Possible Elevated Filling Pressure [ KOREAN CIRCULATION JOURNAL ] - 2018.08.01
    17. Cryptogenic Stroke and High-Risk Patent Foramen Ovale The DEFENSE-PFO Trial [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2018.05.22
    18. Impact of a Geometric Correction for Proximal Flow Constraint on the Assessment of Mitral Regurgitation Severity Using the Proximal Flow Convergence Method [ Journal of Cardiovascular Ultrasound ] - 2018.03.01
    19. Clinical Characteristics of Korean Patients with Bicuspid Aortic Valve Who Underwent Aortic Valve Surgery [ Korean Circulation Journal ] - 2018.01.01
    20. Performance of a Simplified Dichotomous Phenotypic Classification of Bicuspid Aortic Valve to Predict Type of Valvulopathy and Combined Aortopathy [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2017.12.01
    21. Response by Choi et al to Letters Regarding Article, "Dipeptidyl Peptidase-4 Induces Aortic Valve Calcification by Inhibiting Insulin-Like Growth Factor-1 Signaling in Valvular Interstitial Cells" [ CIRCULATION ] - 2017.10.24
    22. In vivo assessment of aortic root geometry in normal controls using 3D analysis of computed tomography [ EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING ] - 2017.07.01
    23. Dipeptidyl Peptidase-4 Induces Aortic Valve Calcification by Inhibiting Insulin-Like Growth Factor-1 Signaling in Valvular Interstitial Cells [ CIRCULATION ] - 2017.05.16
    24. Differential Diagnosis of a Left Atrial Mass after Surgical Excision of Myxoma: a Remnant or a Thrombus? [ Korean Circulation Journal ] - 2016.11.01
    25. Impact of Valvuloarterial Impedance on Concentric Remodeling in Aortic Stenosis and Its Regression after Valve Replacement [ Journal of Cardiovascular Ultrasound ] - 2016.09.01
    26. Infective endocarditis involving an apparently structurally normal valve: new epidemiological trend? [ Korean Journal of Internal Medicine ] - 2015.07.01
    27. Bicuspid Aortic Valve: Unresolved Issues and Role of Imaging Specialists [ Journal of Cardiovascular Ultrasound ] - 2015.03.01
    28. Infective Endocarditis Involving Apparently Structurally Normal Valves in Patients Without Previously Recognized Predisposing Heart Disease [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2015.01.27
    29. Update in acute aortic syndrome: Intramural hematoma and incomplete dissection as new disease entities. [ Journal of Cardiology ] - 2014.09.01
    30. Aortic valve adaptation to aortic root dilatation: insights into the mechanism of functional aortic regurgitation from 3-dimensional cardiac computed tomography. [ Circulation-Cardiovascular Imaging ] - 2014.09.01
    31. Prognostic implications of initial echocardiographic findings in adolescents and adults with supracristal ventricular septal defects [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2014.09.01
    32. Role of noninvasive imaging modalities to better understand the mechanism of left ventricular outflow tract obstruction and tailored lesion-specific treatment options. [ CIRCULATION JOURNAL ] - 2014.08.01
    33. Transcatheter Closures for Fistula Tract and Paravalvular Leak after Mitral Valve Replacement and Tricuspid Annuloplasty [ 대한순환기학회 ] - 2014.01.01
    34. Bicuspid aortic valve phenotype and aortopathy: nomenclature and role of aortic hemodynamics [ JACC-Cardiovascular Imaging ] - 2013.08.01
    35. Determinants of Left Ventricular Vortex Flow Parameters Assessed by Contrast Echocardiography in an In Vivo Animal Model [ ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES ] - 2013.05.01
    36. Association Between Bicuspid Aortic Valve Phenotype and Patterns of Valvular Dysfunction and Bicuspid Aortopathy [ JACC-Cardiovascular Imaging ] - 2013.02.01
    37. Evaluation of left ventricular diastolic function after valve replacement in aortic stenosis using exercise doppler echocardiography [ CIRCULATION JOURNAL ] - 2012.12.01
    38. Aortopathy and bicuspid aortic valve: haemodynamic burden is main contributor to aortic dilatation. [ HEART ] - 2012.12.01
    39. Dissecting pharmacodynamics to determine the optimal sampling time and measurement for assessing the antiplatelet effect of clopidogrel [ JOURNAL OF THROMBOSIS AND HAEMOSTASIS ] - 2012.10.31
    40. Factors Determining Outcomes of Aortic Valve Surgery in Patients with Aortic Regurgitation Due to Behcet's Disease: Impact of Preoperative Echocardiographic Features [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2011.09.01
    41. Prognostic Value of Echocardiographic Estimation of Pulmonary Vascular Resistance in Patients with Acute Pulmonary Thromboembolism [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2011.06.01
    42. Distal Aortic Intramural Hematoma: Clinical Importance of Focal Contrast Enhancement on CT Images [ RADIOLOGY ] - 2011.04.01
    43. Right ventricular remodeling determines tricuspid valve geometry and the severity of functional tricuspid regurgitation: a real-time 3-dimensional echocardiography study. [ Korean Circulation Journal ] - 2010.10.01
    44. Association Between anatomic Features of Atrial Septal Abnormalities Obtained by Omni-Plane Transesophageal Echocardiography and Stroke Recurrence in Cryptogenic Stroke patients with patient Foramen Ovale [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2010.07.01
    45. Long-term outcomes of percutaneous mitral balloon valvuloplasty versus open cardiac surgery [ JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY ] - 2010.01.01
    46. Factors associated with development of late significant tricuspid regurgitation after successful left-sided valve surgery [ HEART ] - 2009.06.01
    47. Restenosis and adverse clinical events after successful percutaneous mitral valvuloplasty: immediate post-procedural mitral valve area as an important prognosticator [ EUROPEAN HEART JOURNAL ] - 2009.05.30
    48. Apical Rotation Assessed by Speckle-Tracking Echocardiography as an Index of Global Left Ventricular Contractility [ CIRCULATION-CARDIOVASCULAR IMAGING ] - 2009.03.01
    49. Echocardiographic diagnosis of right atrial perforation due to primary cardiac angiosarcoma using hand-agitated saline contrast [ 한국심초음파학회 ] - 2008.10.01
    50. Three-dimensional characteristics of functional mitral regurgitation in patients with severe left ventricular dysfunction: a real-time three-dimensional colour Doppler echocardiography study [ HEART ] - 2008.09.24
    51. Prediction of Left Ventricular Remodeling After Primary Reperfusion Therapy in Acute Anterior Wall Myocardial Infarction Using Myocardial Deformation Data [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2008.09.01
    52. Left Atrial Volume Measured by Real-Time 3-Dimensional Echocardiography Predicts Clinical Outcomes in Patients with Severe Left Ventricular Dysfunction and in Sinus Rhythm [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2008.05.01
    53. Geometric and hemodynamic determinants of functional tricuspid regurgitation; A real-time three-dimensional echocardiography study [ INTERNATIONAL JOURNAL OF CARDIOLOGY ] - 2008.02.01
    54. Different gene expression patterns in the lungs of patients with secondary pulmonary hypertension [ Korean Circulation Journal ] - 2008.01.01
    55. Long-term predictors of descending aorta aneurysmal change in patients with aortic dissection [ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ] - 2007.01.02
    56. Factors associated with in-hospital mortality in patients with acute aortic syndrome involving the ascending aorta [ INTERNATIONAL JOURNAL OF CARDIOLOGY ] - 2007.01.02
    57. Long-term outcomes of significant mitral regurgitation after percutaneous mitral valvuloplasty [ CIRCULATION ] - 2006.10.19
    58. 용적 과부하가 동반된 판막질환에서 수술 후 좌심실 수축기능 예측을 위한 2-dimensional longitudinal strain의 유용성 [ ] - 2006.04.01
    59. 병원 획득성 감염성 심내막염의 임상상에 관한 연구 [ ] - 2006.04.01
    60. Usefulness of ventricular longitudinal contractility assessed by Doppler tissue imaging in the prediction of reverse remodeling in patients with severe left ventricular systolic dysfunction. [ ] - 2006.02.01
    61. Assessment of papillary muscle function in patienst with inferior wall myocardial infarction using Doppler tissue imaging [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2005.08.26
    62. Left ventricular apical ballooning due to severe physical stress in patients admitted to the medical ICU [ CHEST ] - 2005.07.26
    63. Excellent results for atrial fibrillation surgery in the presence of giant left atrium and mitral vavle disease [ EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY ] - 2004.08.01
    64. Diagnosis of viable myocardium using velocity data of Doppler myocardial imaging: comparison with positron emission tomography [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2004.03.01
    65. Diagnosis of aortic intramural haematoma [ BRITISH MED JOURNAL PUBL GROUP, BRITISH MED ASSOC HOUSE,TAVISTOCK SQUARE, LONDON, ENGLAND, WC1H 9JR ] - 2004.02.28
    66. Echocardiographic and clinical characteristics of aortic regurgitation because of systemic vasculitis [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2003.10.01
    67. Usefulness of the initial noninvasive imaging study to predict the adverse outcomes in the medical treatment of acute type A aortic intramural hematoma [ CIRCULATION ] - 2003.09.09
    68. 중증 간경화 환자에서 조영 심초음파 기법으로 진단된 저산소혈증이 동반되지 않은 폐내 좌-우 단락의 빈도와 임상적 의의 [ 순환기 ] - 2003.03.01
    69. Comparison of clinical and echocardiographic outcomes after valve repair: degenerative versus rheumatic mitral regurgitation [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2003.03.01
    70. Temporal changes and histologic relation of postsystolic thickening in an animal model of acute ischemia and reperfusion [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2003.03.01
    71. Clinical usefulness of non-invasive measurement of coronary flow velocity reserve with transthoracic dopple echocardiography for detection of restenosis after revascularization of left anterior descen [ 순환기 ] - 2003.03.01
    72. Outcome of significant functional tricuspid regurgitation after percutaneous mitral valvuloplasty [ AMERICAN HEART JOURNAL ] - 2003.03.01
    73. Prognostic implication of ergonovine echocardiography in patients with near normal coronary angiogram or negative stress test for significant fixed stenosis [ JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ] - 2002.11.01
    74. Clinical significance of echo-free space detected by transesophageal echocardiography in patients with type B aortic intramural hematoma [ AMERICAN JOURNAL OF CARDIOLOGY ] - 2002.03.01

    연구과제 수주실적

    1. 인공 판막 치환 후 발생한 유의한 판막 주위 역류에 대하여 경피적 기구 폐쇄술의 유효성 및 안전성을 확인하기 위한 전향적 등록 관찰 연구 - 2021.08.16 ~ 2028.08.31
    2. 새로운 심초음파 기법을 이용한 승모판 폐쇄부전증 중증도의 정량적 평가 - 2021.01.07 ~ 2022.12.31
    3. 관상동맥우회로술 환자의 후향적 다기관 레지스트리 연구 - 2020.01.01 ~ 2023.02.28
    4. 고위험 난원공 개존증을 가진 원인 미상의 고령의 뇌경색 환자에서의 심방 세동의 유병률 및 임상적 영향 평가 - 2019.08.22 ~ 2024.09.30
    5. 석회화가 동반된 대동맥판막 질환 환자에서 혈중 autotaxin 활성도와 질환의 중증도 및 진행과의 연관성 - 2019.07.31 ~ 2023.05.31
    6. 석회화가 동반된 대동맥판막 질환 및 대동맥판막 협착증 환자를 대상으로 DA 1229 의 유효성 및 안전성을 평가하기 위한 다기관, 이중눈가림, 위약 대조, 층화 무작위배정, 평행 비교, 치료적 탐색 임상시험 - 2019.07.30 ~ 2023.06.30
    7. 18F-Sodium Fluoride Positron emission tomography를 통한 대동맥판막 협착증의 판막석회화 및 심근비후 평가 - 2018.06.18 ~ 2020.12.31
    8. 대동맥판막 협착증 및 심근 섬유화 치료제로서 신규한 DPP-4 저해제 개발 연구 - 2017.04.17 ~ 2017.12.31
    9. 대동맥판막 협착증 치료제로서 DPP4 저해제의 적응증 확대 및 임상 진입을 위한 연구 - 2017.02.01 ~ 2019.01.31
    10. Evogliptin의 심장판막석회화에 대한 유효성 평가 - 2016.01.01 ~ 2016.12.31
    11. 대동맥판막 협착증 환자에서 석회화 및 심근 섬유화에 관여하는 신규 표적 단백질 발굴 및 치료제 개발 - 2015.01.01 ~ 2015.08.31
    12. 한국인 이엽성 대동맥판 코호트 구축을 위한 전향적 다기관 등록 연구 - 2014.01.06 ~ 2015.12.31
    13. 이엽성 대동맥 판막 환자에서 고위험 군을 선별할 수 있는 유전적 이상 발굴 및 상호 관계 규명 - 2014.01.01 ~ 2014.12.31
    14. 대동맥판막 협착증 환자에서 석회화 및 심근 섬유화에 관여하는 신규 표적 단백질 발굴 및 치료제 개발 - 2014.01.01 ~ 2014.12.31
    15. 대동맥판막 석회화 과정의 생체표지자에 대한 관찰연구 - 2013.05.10 ~ 2015.04.30
    16. 경.중등도의 본태성 고혈압 환자에서 Fimasartan 30mg의 24시간 혈압 강하 효과를 탐색하기 위한 무작위배정, 양측눈가림, Valsartan 80mg 참조군병행 치료적 탐색 임상시험 - 2013.03.04 ~ 2014.06.30
    17. 심초음파 및 자기공명영상의 다각적 영상 기법을 이용한 승모판 폐쇄부전 환자의 예후 예측 인자 발굴 - 2013.01.11 ~ 2014.12.31
    18. 이엽성 대동맥 판막 환자에서 고위험 군을 선별할 수 있는 유전적 이상 발굴 및 상호 관계 규명 - 2013.01.01 ~ 2013.12.31
    19. 이엽성 대동맥 판막 환자에서 고위험 군을 선별할 수 있는 유전적 이상 발굴 및 상호 관계 규명 - 2012.01.01 ~ 2013.12.31
    20. 좌심실 혈류 소용돌이 분석을 통한 새로운 심장 기능 평가 지표의 개발 - 2010.03.01 ~ 2021.03.31
    21. 심초음파로 측정된 좌심실 torsion과 다른 좌심실 수축기능 지수들과의 상관관계: 급성 심근허혈 동물 모델을 이용한 연구 - 2007.03.01 ~ 2009.12.31
    22. 심박동기 삽입후 우심실 전극 위치에 따른 심실 비동기화 및 수축 기능 변화의 비교; 심초음파를 이용한 다기관 전향적 연구 - 2007.03.01 ~ 2021.03.31
    23. 다양한 신장질환에 의한 폐동맥 고혈압증 환자에서 유전자 발현형태에 관한 연구:폐조직을 이용한 gene microarray analysis - 2004.10.01 ~ 2006.09.30
    24. 고혈압환자에서 운동에 따른 좌심실 이완기능 지표 및 혈중 B-Type natriuretic peptide의 변화에 대한 연구 - 2003.08.01 ~ 2004.07.31
    25. 대동맥 판막질환에서의 심비대 : 심근 조직을 이용한 형태학적 연구-대한순환기학회 - 2001.09.01 ~ 2002.12.31
    26. 내과적 치료를 받는 대동맥 박리와 대동맥벽 혈중환자들의 자연경과에 관한 다기관 경시적 추적관찰 연구 - 1998.10.01 ~ 2000.09.30

    특허/기술이전실적

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    국내외 경력

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