| 교수진 명단
관련/관심분야
데이터가 없습니다.
주요논문
- IDF-11774 Induces Cell Cycle Arrest and Apoptosis by Inhibiting HIF-1α in Gastric Cancer [ Pharmaceutics ] - 2023.12.13
- Escherichia coli adhesion protein FimH exacerbates colitis via CD11b+CD103- dendritic cell activation [ Frontiers in immunology ] - 2023.11.22
- USP14 inhibition regulates tumorigenesis by inducing apoptosis in gastric cancer [ BMB Reports ] - 2023.08.31
- Lipid Nanocarrier-Based Drug Delivery Systems: Therapeutic Advances in the Treatment of Lung Cancer [ INTERNATIONAL JOURNAL OF NANOMEDICINE ] - 2023.05.18
- Suppression of Lung Cancer Malignancy by Micellized siRNA through Cell Cycle Arrest [ ADVANCED HEALTHCARE MATERIALS ] - 2023.04.12
- Pyropia yezoensis-derived porphyran attenuates acute and chronic colitis by suppressing dendritic cells [ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES ] - 2023.03.15
- How Advanced are Cancer Immuno-Nanotherapeutics? A Comprehensive Review of the Literature [ International Journal of Nanomedicine ] - 2023.01.05
- Polysaccharides from Astragalus membranaceus elicit T cell immunity by activation of human peripheral blood dendritic cells [ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES ] - 2022.12.31
- Targeting Cdc20 for cancer therapy [ BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER ] - 2022.11.01
- Cancer immunotherapy by immune checkpoint blockade and its advanced application using bio-nanomaterials [ SEMINARS IN CANCER BIOLOGY ] - 2022.11.01
- Lamin-A/C Is Modulated by the Involvement of Histamine-Mediated Calcium/Calmodulin-Dependent Kinase II in Lung Cancer Cells [ INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ] - 2022.08.13
- Role of Vascular Endothelial Cell Growth Factor on Pathophysiology of Uterine Adenomyosis [ Clinical and Experimental Obstetrics & Gynecology ] - 2022.06.07
- Modulating the Ubiquitin?Proteasome System: A Therapeutic Strategy for Autoimmune Diseases [ Cells ] - 2022.03.24
- Chloride channels and transporters: Roles beyond classical cellular homeostatic pH or ion balance in cancers. [ Cancers ] - 2022.02.09
- Immunomodulatory effects of polysaccharides from marine algae for treating cancer, infectious disease, and inflammation [ PHYTOTHERAPY RESEARCH ] - 2022.02.01
- Ubiquitin Activating Enzyme UBA6 Regulates Th1 and Tc1 Cell Differentiation [ Cells ] - 2022.01.04
- The Ubiquitin System: An Emerging Therapeutic Target for Lung Cancer [ INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ] - 2021.09.06
- Enhancement of Immune Checkpoint Inhibitor-Mediated Anti-Cancer Immunity by Intranasal Treatment of Ecklonia cava Fucoidan against Metastatic Lung Cancer [ INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ] - 2021.09.01
- Ecklonia cava fucoidan has potential to stimulate natural killer cells in vivo [ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES ] - 2021.08.31
- Ubiquitin-Conjugating Enzymes in Cancer [ CELLS ] - 2021.06.04
- Sequential ubiquitination of p53 by TRIM28, RLIM, and MDM2 in lung tumorigenesis [ CELL DEATH AND DIFFERENTIATION ] - 2021.06.01
- Comparison of human peripheral blood dendritic cell activation by four fucoidans [ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES ] - 2021.03.31
- Hif-1 alpha Inhibitors Could Successfully Inhibit the Progression of Differentiated Thyroid Cancer in Vitro [ PHARMACEUTICALS ] - 2020.09.25
- Nucleic acid nanotechnology for cancer treatment [ BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER ] - 2020.08.01
- Universally applicable RNA membrane-based microneedle system for transdermal drug delivery [ MATERIALS HORIZONS ] - 2020.05.01
- Inhibitory effect of porphyran on lipopolysaccharide-induced activation of human immune cells [ CARBOHYDRATE POLYMERS ] - 2020.03.15
- Cancer classification of single-cell gene expression data by neural network. [ BIOINFORMATICS ] - 2020.03.01
- BRC-mediated RNAi targeting of USE1 inhibits tumor growth in vitro and in vivo [ BIOMATERIALS ] - 2020.02.01
- Agonist Antibody Converts Stem Cells into Migrating Brown Adipocyte-Like Cells in Heart. [ Cells ] - 2020.01.20
- USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In Vitro [ INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ] - 2019.10.24
- Phosphate-Functionalized Stabilized F127 Nanoparticles: Introduction of Discrete Surface Charges and Electrophoretic Determination of Aggregation Number [ MACROMOLECULAR RESEARCH ] - 2019.07.01
- Early-stage paired housing improves social interaction in neuronal Uba6-deficient mice [ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ] - 2019.06.25
- Dye encapsulated polymeric nanoprobes for in vitro and in vivo fluorescence imaging in panchromatic range [ JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY ] - 2019.05.25
- Inhibition of peroxiredoxin 2 suppresses Wnt/β-catenin signaling in gastric cancer [ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ] - 2019.04.30
- Activation of Human Dendritic Cells by Ascophyllan Purified from Ascophyllum nodosum [ Marine Drugs ] - 2019.01.19
- Rehmannia glutinosa polysaccharide functions as a mucosal adjuvant to induce dendritic cell activation in mediastinal lymph node [ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES ] - 2018.12.01
- Rehmannia glutinosa polysaccharide promoted activation of human dendritic cells [ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES ] - 2018.09.01
- Immunostimulatory Agent Evaluation: Lymphoid Tissue Extraction and Injection Route-Dependent Dendritic Cell Activation [ JOVE-JOURNAL OF VISUALIZED EXPERIMENTS ] - 2018.09.01
- Administration of Soft Matter Lipid-DNA Nanoparticle As the Immunostimulant via Multiple Routes of Injection in Vivo [ ACS Biomaterials Science & Engineering ] - 2017.09.11
- Ultrasensitive Detection of Oligonucleotides: Single-Walled Carbon Nanotube Transistor Assembled by DNA Block Copolymer [ JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY ] - 2017.08.01
- Rehmannia glutinosa polysaccharide induces toll-like receptor 4 dependent spleen dendritic cell maturation and anti-cancer immunity [ OncoImmunology ] - 2017.05.12
- Time-dependent effect of E. coli LPS in spleen DC activation in vivo: Alteration of numbers, expression of co-stimulatory molecules, production of pro-inflammatory cytokines, and presentation of antigens. [ MOLECULAR IMMUNOLOGY ] - 2017.03.09
- Association of Uba6-Specific-E2 (USE1) With Lung Tumorigenesis [ JOURNAL OF THE NATIONAL CANCER INSTITUTE ] - 2017.03.01
- Dispersion and Stabilization of Quantum Rod Through Semi-interpenetrating Network Formation [ POLYMER-KOREA ] - 2016.01.25
- Purification, sequencing and evaluation of a divergent phytase from Penicillium oxalicum KCTC6440 [ JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY ] - 2015.09.17
- Impairment of social behavior and communication in mice lacking the Uba6-dependent ubiquitin activation system [ BEHAVIOURAL BRAIN RESEARCH ] - 2015.03.15
- Characterization, Gene Cloning, and Sequencing of a Fungal Phytase, PhyA, From Penicillium oxalicum PJ3 [ PREPARATIVE BIOCHEMISTRY BIOTECHNOLOGY ] - 2015.01.01
- Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system [ MOLECULAR CELL ] - 2013.04.25
- Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8 [ PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA ] - 2011.12.20
- Alternative Ubiquitin Activation/Conjugation Cascades Interact with N-End Rule Ubiquitin Ligases to Control Degradation of RGS Proteins [ MOLECULAR CELL ] - 2011.08.05
- Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells. [ JOURNAL OF LIPID RESEARCH ] - 2010.01.01
연구과제 수주실적
- TRIM28-SOCS3 복합체의 작용기작 규명을 통한 폐암 진단 및 제어 기술 연구 - 2024.03.01 ~ 2025.02.28
- 유비퀴틴 네트워크 조절을 통한 폐암제어 연구실 - 2024.03.01 ~ 2025.02.28
- 유비퀴틴 네트워크 조절을 통한 폐암제어 연구실 - 2023.03.01 ~ 2024.02.29
- TRIM28-SOCS3 복합체의 작용기작 규명을 통한 폐암 진단 및 제어 기술 연구 - 2023.03.01 ~ 2024.02.29
- 유비퀴틴 결합효소 TRIM28 작용기작 규명을 통한 난치성 폐암 제어 기술 연구 - 2022.03.01 ~ 2023.02.28
- 유비퀴틴 조절을 통한 폐암제어 연구실(3) - 2022.03.01 ~ 2023.02.28
- UBA6 저해 폐암치료제 기전연구 - 2022.01.01 ~ 2022.12.31
- UBA6 저해 폐암치료제 기전연구 - 2021.11.01 ~ 2021.12.31
- 유비퀴틴 조절을 통한 폐암제어 연구실(2) - 2021.06.01 ~ 2022.02.28
- 유비퀴틴 결합효소 TRIM28 작용기작 규명을 통한 난치성 폐암 제어 기술 연구 - 2021.03.01 ~ 2022.02.28
- 유비퀴틴 조절을 통한 폐암제어 연구실(1) - 2020.07.01 ~ 2021.05.31
- 유비퀴틴 결합효소 TRIM28 작용기작 규명을 통한 난치성 폐암 제어 기술 연구 - 2020.03.01 ~ 2021.02.28
- 유비퀴틴 결합효소 TRIM28 작용기작 규명을 통한 난치성 폐암 제어 기술 연구 - 2019.09.01 ~ 2020.02.29
- 폐암 조기진단 바이오마커로서 UBA6-USE1의 네트워크 규명 - 2019.03.01 ~ 2019.05.31
- UBA6 네트워크 억제를 통한 폐암 저해제 개발(3) - 2019.01.01 ~ 2019.12.31
- USE1 압타머 개발을 통한 폐암진단 기술 개발 - 2019.01.01 ~ 2019.12.31
- 폐암 조기진단 바이오마커로서 UBA6-USE1의 네트워크 규명 - 2018.04.01 ~ 2019.02.28
- 브레인프리즘 기반 신경회로 유전자 및 단백질 지도 구축 - 2018.03.01 ~ 2018.12.31
- BRC 조직을 이용한 폐암, 위암에서의 새로운 바이오마커 개발 - 2018.01.01 ~ 2018.12.31
- UBA6 네트워크 억제를 통한 폐암 저해제 개발(2) - 2018.01.01 ~ 2018.12.31
- 줄기세포 유래 맞춤형 융복합 NK 세포치료제 개발 - 2017.10.16 ~ 2018.10.15
- 폐암 조기진단 바이오마커로서 UBA6-USE1의 네트워크 규명 - 2017.06.01 ~ 2018.03.31
- 브레인프리즘 기반 신경회로 유전자 및 단백질 지도 구축 - 2017.06.01 ~ 2018.02.28
- UBA6 네트워크 억제를 통한 폐암 저해제 개발(1) - 2017.04.01 ~ 2017.12.31
- 줄기세포 유래 맞춤형 융복합 NK 세포치료제 개발 - 2017.02.16 ~ 2017.10.15
- 폐암 조기진단 바이오마커로서 UBA6 조절 네트워크의 규명 - 2017.01.01 ~ 2017.12.31
- BRC 조직을 이용한 폐암 위암에서의 새로운 바이오마커 개발 - 2017.01.01 ~ 2017.12.31
- 위암에서의 새로운 유비퀴틴 작용기작의 규명 및 바이오마커 개발 - 2016.11.28 ~ 2021.12.31
- 폐암 조기진단 바이오마커로서 UBA6-USE1의 네트워크 규명 - 2016.06.01 ~ 2017.05.31
- Uba6 뇌특이적 낙아웃 마우스를 이용한 엔젤만 증후군의 작용기작 규명 - 2016.01.01 ~ 2016.12.31
- 알짜하이머병에 관여하는 Uba6의 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2015.11.01 ~ 2016.10.31
- Uba6~Use1의 대한 핵심 표적 단백질들의 확인 및 작용기작 규명(3) - 2015.06.01 ~ 2016.05.31
- 알쯔하이머병에 관여하는 Uba6의 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2015.01.01 ~ 2015.12.31
- Uba6~Use1의 대한 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2015.01.01 ~ 2015.12.31
- 알짜하이머병에 관여하는 Uba6의 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2014.11.01 ~ 2015.10.31
- Uba6~Use1의 대한 핵심 표적 단백질들의 확인 및 작용기작 규명(2) - 2014.06.01 ~ 2015.05.31
- 알쯔하이머병에 관여하는 Uba6의 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2014.01.01 ~ 2014.12.31
- Uba6~Use1의 대한 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2014.01.01 ~ 2014.12.31
- 알짜하이머병에 관여하는 Uba6의 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2013.11.01 ~ 2014.10.31
- Uba6~Use1의 대한 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2013.06.01 ~ 2014.05.31
- Uba6~Use1의 대한 핵심 표적 단백질들의 확인 및 작용기작 규명 - 2013.03.01 ~ 2013.12.31
특허/기술이전실적
- 대장균 부착 단백질 FimH를 유효성분으로 포함하는 항암 면역 증강용 조성물 - 2022.12.01
- 자기 조립 화합물을 포함하는 항-동결 조성물 - 2021.07.01
- 갈색지방세포 분화 유도 항체 및 이를 유효성분으로 포함하는 대사성 질환 예방 또는 치료용 조성물 - 2021.01.05
- sIPN 구조가 코어에 형성된 형광 이미징용 표지나노입자 - 2017.12.11
- 암 진단마커로서 Uba6 또는 Use1의 용도 - 2017.05.31
국내외 경력
데이터가 없습니다.
공지